Cancer Treatment are suspected to accelerate aging CERTAIN Processe in-the-body. A new study found That Has Suchi Biological indicators of aging correlate With Decline in cognitive function in Celebs Who thought undergone Breast Cancer Years Earlier severals TREATMENT. Published early online in Cancer, A journal of peer-reviewed studies-the American Cancer Society, the-Findings point to an aging-like effect of Cancer Treatment and cognitive Decline Further Connect to Print.
Treatment for Breast Cancer Increase patients' Risks for long-term and late toxicities, includingï¼ persistent fatigue, Pain, and cognitive dysfunction. Certain Treatment, includingï¼ radiation and some chemotherapeutic drugs, work by damaging DNA-the cells of Cancer, pocket They can ALSO Cause Damage to DNA of normal cells, Which can contribute to ACCELERATED Biological aging.
To examine WHETHER Biological indicators of aging are Related to cognitive function in Breast Cancer survivors, Judith E. Carroll, PhD, Associate Professor of Psychiatry, of-the UCLA Cousins Center for Psychoneuroimmunology And The Semel Institute for Neuroscience and Human Behavior, and her colleagues Evaluated a group of 94 Celebs Who thought Been treated for Breast Cancer Earlier three to six-years. The indicators included elevated aging of Biological Damage Levels of DNA, Reduced Enzymatic telomerase activity, and Shorter telomere length in blood cells LEAD. (The Telomerase That is an enzyme important for Maintaining-the length of telomeres, Repeat sequences of DNA at-the ends of chromosome That Maintain help-the health of cells and SERVE as a marker of cell Age.)
The team found Celebs Who That thought Previously Been treated for Breast Cancer Who thought DNA Damage Both Higher and lower telomerase activity thought lower executive function scores. In Addition, lower telomerase activity Was Associated With worse attention and motor speed. Telomere length was not Related to ANY of-the neurocognitive domains.
"These are important because Findings Provide Further information about What They mights an after BE happenings That TREATMENT Cancer Decline in some cognitive impacts an individual. Print information can INFORM future May lead to new Research and Intervention To Prevent These cognitive Decline," said Dr. Carroll, a member of Who the ALSO-the UCLA Jonsson Comprehensive Cancer Center. "The work by identifying the key Novel Biological Factors in aging and cognitive function Connecting to them, Which initiates new AVENUES of Research."
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