Wednesday , September 28 2022

The twins are still in with altered DNA & # 39; risk of becoming infected with HIV


The twins whose DNA was altered as part of a controversial initiative in China to make them resistant to infection & # 39; HIV, they can still get the virus that causes AIDS. Some relatively rare breeds & # 39; HIV can enter into your cells if the girls are f & # 39; contact & # 39; tissues or fluids contaminated, she said. Robin Shattock, president of the area of ​​mucosal infection and immunity of Imperial College London in the UK.

He Jiankui, the researcher used a technique called Crispr to manipulate the DNA of twins when they were at the embryonic stage & # 39; development, Facing criticism for girls exposure to risks & # 39; potential life that scientists are just beginning to understand. Other Approaches & # 39; widely used prevention are more reliable and less risky than using unproven technique to alter the genome, Shattock explained.

"This approach is totally ridiculous and unnecessary" to prevent & # 39; infections, said the expert in & # 39; telephone interview. "It is questionable ethical." Crispr allows scientists to eliminate or replace specific genes in & # 39; living organisms. While it has good prospects to address a number of & # 39; DNA diseases, scientists are investigating whether circumstances affect people likely to suffer from cancer or other diseases. Many governments have restricted or banned their use in human embryos because the characteristics altered to pass to future generations b & # 39; unknown consequences.

YouTube video

It is, from the University of Science and Technology in the southern city & # 39; Shenzhen, China, announced its work on a video on YouTube and planned to present its data on Wednesday at & # 39; & # 39 in conference, Hong Kong. The university said in & # 39; statement was "shocked" by the actions of & # 39; He, the National Commission of Health of China has requested an investigation, and a group & # 39; 122 Chinese scientists issued a joint statement declaring that the work was "madness".

"I understand that my work will be controversial, but I believe that families need this technology and I am ready to make them critical", said the researcher in the video. Nearly 37 million people worldwide living with HIV, according to the World Health Organization, Although the rate of & # 39; infection of China is one of the lowest. He, who studied in the United States, said the girls' father was infected and he wanted to protect them from HIV.

The transmission from parent to child can & # 39; unblocked by proper use of & # 39; antiviral drugs, Shattock explained. Regime called Prep can & # 39; also prevent people in & # 39; high risk & # 39; infection from being infected by & # 39; other routes. The antiviral treatment & # 39; everyday presents its own risksHe noted in & # 39; another video. HIV remains & # 39; incurable and kills about 1 million people a year, he added.

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