Wednesday , June 23 2021

Parents praises the study of peanut important to show that you can & # 39; to build tolerance to allergies



New research has found that it is possible to build tolerance to peanut allergies.

Parents praised the landmark study, which found that participants usually not able to tolerate exposure to even ten & # 39; allergen eventually cope with & # 39; two whole peanuts.

Children who suffered from severe allergy participated in the trial & # 39; year, which were increasing amounts of & # 39; peanut protein.

Already used to treat pollen, it is hoped that the treatment of & # 39; with immunotherapy therapy can & # 39; protect people from reactions & # 39; threatening, reports the Mirror.

Emily Pratt increased tolerance
Emily Pratt increased tolerance

The woman & # 39; & # 39 girl; six years participated in the trial said it was "completely changed their lives".

Sophie Pratt said: "Before Emily took part were cramped for more than twenty minutes from a hospital and could not attend dates or items & # 39; play without me or my husband was there.

"We had constant studies of food labels to ensure that peanuts have been completely removed from the diet of & # 39; Emily.

Her allergy was severe so even a small amount of & # 39; & # 39 peanuts can; lead to very serious reaction. The impact on our family life was great. "

The girl & # 39; 44, said by the end of the trial & # 39; Emily was able to tolerate about seven years & # 39; peanuts.

The study recruited nearly 500 PALISADE child of & # 39; & # 39 between four; Seventy years since the United States and Europe to take part in the largest trial & # 39; treatment & # 39; peanut allergy.

Participants were divided into groups receiving either capsule & # 39; peanut protein powder or a dummy.

The doses gradually increased every two weeks for a period of & # 39; six months, before continuing on a "dose & # 39; maintenance" of & # 39; peanuts for another six months.

The results, published in the New England Journal of Medicine, found about 67% of children and young people can tolerate at least 600 mg & # 39; peanut protein, compared to & # 39; Only 4% of the participants on placebo dummy.

The study hope to parents
The study hope to parents

Professor George du Toit, a pediatric consultant allergy f & # 39; Evelina London and principal investigator of the study, said: "The peanut allergy is extremely difficult to manage children and their families , because they follow a strict diet without peanuts.

"The families live in fear & # 39; of & # 39; accidental exposure as allergic reactions may be very severe, and can even lead to death.

"Until recently, there was nothing to offer peanut allergy suffering than education on the prevention and recognition of peanuts and treatment of itself & # 39; allergic reactions."

The peanut allergy, a potentially & # 39; a life-threatening condition, doubled in the last twenty years and affects about 1 in 50 children in the UK.

The allergy is rarely peeled and is the most common cause of & # 39; & # 39 deaths; Allergy & # 39; food.

The study was funded by PALISADE Aimmune Therapeutics, which manufactures peanut protein used during the trial, and carried out by researchers from London Evelina Children & # 39; s Hospital and King & # 39; s College London.

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