Monday , May 23 2022

Hormone released during exercise may reduce Alzheimer's



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The iris, the hormone the body separates in & # 39; larger amounts during practice & # 39; physical exercise, can & # 39; prevent loss of & # 39; memory related disease & # 39; Alzheimer's, according to research published in the journal Nature Medicine.

The researchers responsible for this new discovery explain that, when exercising the body, the muscle tissue releasing hormone iris, entering circulation in the body and is able to improve the ability cognitive, according to experts & # 39; Federal University & # 39; Rio de Janeiro. Janeiro and the University & # 39; Columbia in studies with mice with & # 39; that disease.

Now, scientists responsible for this new study showed that the increase in iris, as well as its precursor protein, FNDC5, can reduce memory deficits and learning in & # 39; animals rodents with & # 39; Alzheimer's.

They also noted that when the appearance & # 39; this substance in the brain & # 39; diseased mice was blocked, the cognitive effects of & # 39; benefit & # 39; physical exercise lost.

"These findings offer new insight into the pathogenesis of the disease & # 39; s disease and new directions for the therapeutic strategy," argue the researchers Chen Xu and Li Gan f & # 39; article News and Views about the recent discovery.

"B & # 39; surprising way, the authors found that levels of & # 39; FNDC5 / Iris also be reduced in the brains of & # 39; the normal age at & # 39; patients & # 39; Madness by Atari 39; Lewy body, and suggest broader impact & # 39; of & # 39; this hormone on brain disorders and aging ", the experts conclude.

future Investigations

Scientists said that although the exercise is known to improve cognitive abilities and slow the progression of & # 39; neurodegenerative disorders, are additional studies to better understand how the iris comes in action and interacts with the brain .

In addition, they indicated that more knowledge is needed to assess whether the protein has a cognitive effect & # 39; a similar benefit in humans.

However, they stressed that the recent discovery can & # 39; pave the way for new therapeutic strategies that serve to reduce cognitive deterioration in & # 39; patients & # 39; Alzheimer's, a disease not yet treated.

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