Monday , October 25 2021

The Chilean scientists discover antibodies that protect Hantavirus of & # 39; the Andes



[ad_1]

This discovery can & # 39; also be applied to humans, said María Inés Barría, microbiologist and coordinator & # 39; this research, which began in 2014 and the first findings were published today in the journal Science Translational Medicine.

The hanta virus is an infection that transmit rodents people and subtype & # 39; the Andes, which affects the area of ​​Chilean Patagonia and Argentina, is the only one shown can & # 39; also spread between people.

Andes Hantavirus infection resulting in & # 39; an extremely dangerous condition called pulmonary syndrome & # 39; Hantavirus (SCPH), you can & # 39; causes fever, pain & # 39; headache, low blood pressure and heart failure and lung, which is & # 39; great concern because of the rate & # 39; mortality.

The survivors' antibodies

The results of & # 39; the investigation has shown that the antibodies of the human survivors protect animals from suffering the SCPH even when given after infection & # 39; the Andes Hantavirus.

This suggests that they can be used as a treatment & # 39; prevention & # 39; after exposure to a disease currently not & # 39; & # 39 has options, care, according to research.

"Until now m & # 39; there is no specific treatment for this infection, the only thing that can & # 39; to make the doctor is treating & # 39; support in the ICU," said Barría.

In 2017, 90 people were infected with Hantavirus of & # 39; the Andes, of which 24 died from SCPH.

vulnerable groups

The groups most vulnerable to this infection are people living in & # 39; to work in rural areas or & # 39; forestry and agricultural areas have a higher incidence in young men.

Method & # 39; work & # 39; the investigation was to isolate antibodies & # 39; 27 patients who survived the Hantavirus of & # 39; the Andes or showed mild symptomatology.

The next step was to inject hamsters b & # 39; lethal dose of the virus and then give them the human antibodies, and f & # 39; each of them has been avoided and SCPH survived.

"The hamsters were used because it is the model that most closely resembles the symptomatology and pathology of humans", explained Barría.

Currently, the University & # 39; Concepción is also developing dose is suitable for people and b & # 39; so you can & # 39; in a clinical trial testing the effects of & # 39; those isolated antibodies that were so & # 39; success in rodents.

Also, once proved that the method prevents the development of & # 39; SCPH once infected by Hantavirus Andes, scientists want to study in mice if also works to prevent infection & # 39; this virus.

"Our idea is to nittestjawha also as a prophylactic with & # 39; animals, to take a dose before infection, so we will increase the spectrum of & # 39; action & # 39; these antibodies" , added Barría, who hopes to b & # 39; this finding can & # 39; develop a substance that prevents infection.

The expert indicated it can & # 39; serves as a "short-term vaccine" by the feature & # 39; antibodies "people are protected for a short period & # 39; time".

"Even if the protection lasts for three weeks or two months, would also be useful for & # 39; risk groups: forestry workers, agricultural workers, tourists went to Patagonia or even face a major outbreak & # 39; hanta ".

The researcher also specified that this discovery can & # 39; to care for other types of & # 39; hanta present in Europe and Asia.

"The problem is not technology, desire or ideas, but the funding that we need, to know where you & # 39; go to this investigation", concluded Barría.

<! – Download the annex document & # 39; this news ->

[ad_2]
Source link