Saturday , June 25 2022

They create small placentas to study the disease during pregnancy


Researchers – University & # 39; Cambridge published today in the journal Nature study innovative techniques to analyze the development of human placenta by & # 39; laboratory cultures, which will raise awareness about the disease during pregnancy.

The process consists in creating & # 39; organoids, ie & # 39; miniature models & # 39; organ developed in the laboratory and allow you to know better how to develop placenta during pregnancy.

B & # 39; this way, many disorders that occur during this process can be studied, such as preeclampsia, the growth restriction and fetal death, arising from abnormal growth of fetus inside the placenta during the first trimester.

Until now knowledge of the human placenta has been limited by the lack of & # 39; functional models created in the laboratory experimented with, to the development of & # 39; organoids allow expanded investigations in & # 39; this area.

The scientists, led by Professor of the University & # 39; Cambridge, Ashley Moffett, used the term generation & # 39; organ cultures created by trofobastati cells are extracted from the placenta during the first trimester, between six and nine & # 39; weeks gestation

The crop & # 39; grew by & # 39; quickest and developed three-dimensional organoidali structures during the first fifteen days, and even three selected crops b & # 39; randomized continued to grow well next year.

These organoids also allow the study of the physiological, metabolic and hormonal changes that occur during pregnancy.

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