Saturday , June 25 2022

They create small placentas to study the disease during pregnancy



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Press Lara | EFEGroup & # 39; researchers from the University & # 39; Cambridge published Wednesday in the journal Nature study innovative technique to analyze the development of human plakda through & # 39; laboratory cultures, which will increase knowledge about diseases arise & # 39; during pregnancy.

The process consists in creating & # 39; organoids, ie & # 39; miniature models & # 39; organ developed in the laboratory and allow you to know better how to develop placenta during pregnancy.

B & # 39; this way, we studying various disorders that occur during this process such as preeclampsia, the growth restriction and the death of the fetus, which originated from abnormal growth of the fetus inside the placenta during the first trimester.

Until now knowledge of the human placenta has been limited by the lack of & # 39; functional models created in a laboratory experiment which could, to the development of & # 39; organoids allows to expand investigations into & # 39; this area.

The scientists, led by Professor of the University & # 39; Cambridge, Ashley Moffett, used the term generation & # 39; organ cultures created by trofobastati cells are extracted from the placenta during the first trimester, between six and nine & # 39; weeks gestation

The crop & # 39; grew by & # 39; rapid rate and developed a three-dimensional organoidali structures during the first fifteen days, and even three selected crops b & # 39; randomized continued to grow well next year.

These organoids also allow the study of the physiological, metabolic and hormonal changes that occur during pregnancy.

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