Some more than others, but with & # 39; generally the majority of men have hair in & # 39; areas of the body size head, legs or arms. However, in & # 39; others, such as the hand palms or feet feet, not the slightest hint of & # 39; born hair, regardless of gender, age or trend individual hair. Why is this?
This is a question that many scientists questioned and now team & # 39; researchers from University & # 39; Pennsylvania School of Medicine, With the aim of applying this knowledge to treat & # 39; alopecia or recovery of hair growth in Scars from burns and large wounds. Moreover, its results, which were published in today & # 39; Malta Reports Cells, Explain why some animals, like rabbits, Have hair on body areas other rodents, Such as mice, no.
Inhibition & # 39; more signs "hairless"
The gene encoding inhibitor of the passage of & # 39; signaling involved in the development of hair follicles is expressed on the palms of the hands and feet toes
These researchers focused their study Binary WNT signaling, Known to be essential role in – development & # 39; hair follicles and hair growth. Clearly, f & # 39; normal conditions, this route works perfectly in & # 39; areas of the body such as the legs or arms, but does not work in & # 39; other areas, such as The hand shovels.
The answer, as these scientists describe in their study, located in Inhibitor & # 39; & # 39 protein; that path, called Dickkopf 2 (DDK2). They checked to find the gene that codes for this protein highly expressed in the plantar skin of mice, Which, as in the human feet soles, no hair to grow. However, if inactive the – The hair starts to develop as in the rest of the body. This shows that WNT is also the way in & # 39; these areas, But is paralyzed by & # 39; the action & # 39; DDK2.
Finally, they found that rabbits this gene is expressed, So his skin, like that & # 39; polar bears, so he has hair. This shows that during evolution, this path was followed different paths, According to – concrete needs & # 39; species animal
Beyond the curiosity
All this answer curious question we have done for a long time, but the goal of & # 39; this team & # 39; Scientists go much further.
It is known that – hair – follicles develop in – human fetuses, but stop production after birth. That is why, when a large burn or wound heals, The new skin is devoid of hair. In the search for solutions to this problem, they proposed Check whether DDK2 what is involved paralysis in the development of hair follicles; because, if so, in & # 39; these specific cases can & # 39; to be reactivated to encourage new skin to hair.
But, above all, the greatest concern about the lack of & # 39; hair is what & # 39; people who have alopecia. According to data from the Spanish Academy of Dermatology and Venereology (AEDV), 40% of & # 39; men between the ages of & # 39; 18 and 39 suffers androgenic alopecia. In addition, the percentage reaches 95% in men with age & # 39; over 70 years.
Although tissoponix of & # 39; health problems, is often accompanied by a big one not satisfied with the physical aspect, So scientists try to find a solution. Previous studies have found DKK2 as a potential candidates the image of & # 39; this progressive hair loss, so these researchers intend to also focus the next steps of their work in its analysis. Without a doubt, if you manage to achieve good port, many people will be happy for their findings.
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